Mögliche Mechanismen zur Proliferations- und Differentiationskontrolle
作者： H. P. Meinzer , H. J. Baur , B. Sandblad , L. Rodrigues
DOI: 10.1007/978-3-642-48167-3_26
关键词:
摘要: Es wird ein Modell der intestinalen Darmkrypte dargestellt, das mit Hilfe eines Computersimulationsexperiments entwickelt wurde. Dieses vereinigt zwei grundlegende Konzepte Zellproliferations- und Differentiationskontrolle: erstens die Regulation Proliferation (d.h. Kontrolle daruber, ob sich eine teilungsfahige Zelle teilt oder nicht) Differentiation Funktion Zelle) durch zellintern reprasentierte Generationszahl. Zweitens Wiedertierstellung des stabilen Gleichgewichts Zellverbandes nach einer Storung einen inhibitiven Kontrollmechanismus.
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