A water soluble probe with near infrared two-photon absorption and polarity-induced fluorescence for cerebral vascular imaging

作者: Julien Massin , Azzam Charaf-Eddin , Florence Appaix , Yann Bretonnière , Denis Jacquemin

DOI: 10.1039/C3SC22325F

关键词:

摘要: A water soluble Lemke chromophore derivative shows an unusual polarity dependence of its emission efficiency, leading to strong red-NIR fluorescence in when fitted with appropriate water-solubilizing polymer chains. In this edge article, the synthesis is described. The on solvent investigated experimentally and rationalized basis ab initio calculations. Finally, we demonstrate that a valuable candidate for vivo two-photon imaging cerebral vasculature, absorption biological transparency window.

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