Effects of gallopamil and nifedipine on ventricular arrhythmias, ventricular fibrillation, epicardial conduction delays and changes in the ventricular fibrillation threshold with time during myocardial ischaemia and reperfusion

摘要: Malignant ventricular arrhythmias, especially fibrillation, which often occur within minutes after occlusion of a coronary vessel, are the commonest cause sudden cardiac death (1–3). The arrhythmias in animals performed once for 20–30 close to origin vessel show phasic frequency distribution (4, 5). There is build-up between 2nd and 10th minute (phase Ia) 15th 20th Ib). They distinctly less severe interval two phases.