Bioactive lichen metabolites: alpine habitats as an untapped source

摘要: Lichens are fungal and algal/cyanobacterial symbioses resulting in the production of specific metabolites. Some these forming an available biomass for phytochemical investigations, including assessment biological activities isolated compounds. The alpine or polar region characterised by highly stressful environmental conditions many organisms, but lichens among dominating organisms habitats. In performant mutual protective system, lichen fungi often accumulate high amounts metabolites with physicochemical properties (UV absorbents, hydrophobicity) which help to survive. Unique secondary polysaccharides have been tested from organisms. Even though this has until now only a low number compounds so far, interesting recorded. We review here some antimicrobial, anti-inflammatory, antiproliferative antioxidant described. Solutions axenic biotechnological cultivation each symbiotic partner particularly mycobiont obtain challenging overcome limitations supply rare Additionally, appear harbour diversity culturable microorganisms active also recently.