Micro/nanohybrid hierarchical poly(N‐isopropylacrylamide)/calcium carbonate composites for smart drug delivery
作者： Jun Shi , Wenyan Qi , Chao Du , Jin Shi , Shaokui Cao
DOI: 10.1002/APP.38718
关键词:
摘要: Poly(N-isopropylacrylamide) (PNIPAAm)/calcium carbonate (CaCO3) micro/nanohybrid composites with smart drug-delivery property had been prepared via in situ biomineralization reaction. Sodium poly(styrene sulfonate) (PSS) was used as the crystal growth additive to control crystalline polymorph of CaCO3 and morphology hybrid materials. The interaction between PSS Ca2+ contributed formation hierarchical composites, which microscale vaterite microparticles were covered by nanoscale PNIPAAm micelle. Vitamin B2 (VB2) release behavior found be pH- thermal-responsive. Moreover, profiles sustained introduction microparticles, suggesting that could hinder permeation encapsulated VB2 reduce drug effectively. materials can “smart” for controlled delivery. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013
sci-hub.se 参考文章(35)
Ximeng Sun, Jun Shi, Zhengzheng Zhang, Shaokui Cao, Dual-responsive semi-interpenetrating network beads based on calcium alginate/poly(N-isopropylacrylamide)/poly(sodium acrylate) for sustained drug release Journal of Applied Polymer Science. ,vol. 122, pp. 729- 737 ,(2011) , 10.1002/APP.33872
Hua Wei, Xian-Zheng Zhang, Han Cheng, Wen-Qin Chen, Si-Xue Cheng, Ren-Xi Zhuo, Self-assembled thermo- and pH responsive micelles of poly(10-undecenoic acid-b-N-isopropylacrylamide) for drug delivery Journal of Controlled Release. ,vol. 116, pp. 266- 274 ,(2006) , 10.1016/J.JCONREL.2006.08.018
Yi Jin, Wangcai Liu, Jiarong Wang, Jianghua Fang, Haoqi Gao, (Protamine/dextran sulfate)6 microcapules templated on biocompatible calcium carbonate microspheres Colloids and Surfaces A: Physicochemical and Engineering Aspects. ,vol. 342, pp. 40- 45 ,(2009) , 10.1016/J.COLSURFA.2009.03.055
Ling Hu, Zhengwei Mao, Changyou Gao, Colloidal particles for cellular uptake and delivery Journal of Materials Chemistry. ,vol. 19, pp. 3108- 3115 ,(2009) , 10.1039/B815958K
Xu-Rong Xu, An-Hua Cai, Rui Liu, Hai-Hua Pan, Rui-Kang Tang, Kilwon Cho, The roles of water and polyelectrolytes in the phase transformation of amorphous calcium carbonate Journal of Crystal Growth. ,vol. 310, pp. 3779- 3787 ,(2008) , 10.1016/J.JCRYSGRO.2008.05.034
Qingchun Yuan, Olivier J Cayre, Syuji Fujii, Steven P Armes, Richard A Williams, Simon Biggs, None, Responsive core-shell latex particles as colloidosome microcapsule membranes. Langmuir. ,vol. 26, pp. 18408- 18414 ,(2010) , 10.1021/LA1033564
Yuuka Fukui, Keiji Fujimoto, Bio-inspired nanoreactor based on a miniemulsion system to create organic–inorganic hybrid nanoparticles and nanofilms Journal of Materials Chemistry. ,vol. 22, pp. 3493- 3499 ,(2012) , 10.1039/C2JM14661D
Manish K. Jaiswal, Shailee Mehta, Rinti Banerjee, D. Bahadur, A comparative study on thermoresponsive magnetic nanohydrogels: role of surface-engineered magnetic nanoparticles Colloid and Polymer Science. ,vol. 290, pp. 607- 617 ,(2012) , 10.1007/S00396-011-2572-Z
Mingzhen Zhang, Kazunori Kataoka, Nano-structured composites based on calcium phosphate for cellular delivery of therapeutic and diagnostic agents Nano Today. ,vol. 4, pp. 508- 517 ,(2009) , 10.1016/J.NANTOD.2009.10.009
Jun Shi, Xiaopei Liu, Yujun Shang, Shaokui Cao, Biomineralized polysaccharide alginate membrane for multi-responsive controlled drug delivery Journal of Membrane Science. ,vol. 352, pp. 262- 270 ,(2010) , 10.1016/J.MEMSCI.2010.02.026