Extraneuronal Influences Upon the Electrical Activity of Isolated Cortex Following Stimulation of the Reticular Activating System1

摘要: Summary. 1. Electrographic evidence is presented to show that the spontaneous as well (chemically induced) epileptic electrical activity of neuronally completely isolated parietal cortex cat may be influenced by stimulation reticular activating system brain stem. A description given various forms effects recorded. 2. By gross microscopic observation it was found, on intact cortex, cortical circulatory phenomena accompany EEG activation elicited stimulation. these phenomena, most conspicuous feature which a vasodilatation and an increase in speed circulating blood elements. 3. Subjectively, there seemed general direct proportionality between electrographic changes. The changes often closely paralleled time (as cortex). 4. grossly visible were abolished, together with EEG, small doses barbiturates intravenously. 5. mechanisms underlying have been analyzed preliminary way. Such changes, observed after procedures interfering possible pressor caused tegmental diencephalic abolished intercollicular stem section, procedure, however, did not interfere cortex. 6. upon chernically induced discharges provide additional information for understanding arousing stimuli abnormalities thc EEG. 7. results suggest influence means extraneuronal mechanisms. findings indicate factors are involved, but also humoral events primarily responsible recorded.