Phosphodiesterase Type 5 (PDE5) Inhibitors in Erectile Dysfunction: The Proper Drug for the Proper Patient

摘要: ABSTRACT Introduction Erectile dysfunction (ED) is a very common multidimensional disorder affecting men worldwide. Physical illness, reaction to life stresses, or an unhappy couple relationship influence clinical outcome. Phosphodiesterase type 5 (PDE5) inhibitors are recognized as efficacious and well tolerated, the first‐line treatment for ED. Sildenafil, tadalafil, vardenafil most widely used studied PDE5 inhibitors. Data acquired during routine diagnostic workup ED should be taken into account when choosing best inhibitor individual patient, creating individualized plan, going beyond “experience‐based” subjective opinion unfounded ideas prejudice regarding currently available drugs. Aim As process of matching given patient's profile any selected often relies more on physician's personal convictions than solid evidence, aim this review identify main clinical, demographic, relational factors influencing choice Methods A systematic literature search current guidelines were evaluated in manner. Main Outcome Measures The cultural, demographical considered have been identified. Results described. short list items that may help right different patients daily practice has prepared. Conclusions simple algorithms prepared useful tool practice, which each subject affected by Corona G, Mondaini N, Ungar A, Razzoli E, Rossi Fusco F. erectile dysfunction: proper drug patient.