Parental Stress Increases the Detrimental Effect of Traffic Exposure on Children's Lung Function

摘要: Rationale: Emerging evidence indicates that psychosocial stress enhances the effect of traffic exposure on development asthma.Objectives: We hypothesized would also modify lung function deficits.Methods: studied 1,399 participants in Southern California Children's Health Study undergoing testing (mean age, 11.2 yr). used hierarchical mixed models to assess joint traffic-related air pollution and function.Measurements Main Results: Psychosocial each child's household was assessed based parental response perceived scale (range, 0–16) at study entry. Exposures nitric oxide, nitrogen dioxide, total oxides (NOx), surrogates mixture, were estimated schools residences a land-use regression model. Among children from high-stress households (parental >4) deficits FEV1 4.5...