Coffee consumption and digestive tract cancers

摘要: The relationship between coffee drinking and the risk of digestive tract neoplasms was analyzed in a case-control study 50 cases cancer mouth or pharynx, 209 esophagus, 397 stomach, 455 colon, 295 rectum, 151 liver, 214 pancreas, 1944 control subjects admitted for acute, non-digestive disorders. There no significant consistent association cancers pancreas. In particular, pancreatic cancer, multivariate relative risks intermediate upper tertiles were 1.05 1.01, respectively. inverse trends with measures consumption colon rectal cancers, according to being 0.86 0.64 0.97 0.66 rectum. This apparent protection is agreement some (but not all) previous epidemiological evidence finds possible biological interpretation terms interference on bile secretion, causing reduced acid neutral sterol concentrations bowel. conclusion, results this study, major interest which lies opportunity drawing up an overall pattern various neoplasms, offer further reassurance as regards effects carcinogenesis.