Alteration of sperm quality and hormone levels by polycyclic aromatic hydrocarbons on airborne particulate particles.
作者： Hueiwang Anna Jeng , Liang Yu
DOI: 10.1080/10934520801959815
关键词:
摘要: The objective of this study was to assess whether polycyclic aromatic hydrocarbons (PAHs) affect male reproductive functions in vivo. Male parameters included testis weight, sperm counts and motility, circulating follicle-stimulating hormone (FSH), luteinizing (LH), testosterone. average body epididymis weight the exposed group were not significantly lower than that control (p < 0.01). daily numbers PAH-exposed groups those group. motility less Plasma LH concentrations increased at end exposure period continued increase after post-cessation PAHs. Testosterone decreased exposure. However, follicle-stimulation level remained relatively stable during period. present showed PAHs can compromise alter endocrine levels.
sci-hub.se 参考文章(43)
J Toppari, J C Larsen, P Christiansen, A Giwercman, P Grandjean, L J Guillette, B Jégou, T K Jensen, P Jouannet, N Keiding, H Leffers, J A McLachlan, O Meyer, J Müller, E Rajpert-De Meyts, T Scheike, R Sharpe, J Sumpter, N E Skakkebaek, Male reproductive health and environmental xenoestrogens Environmental Health Perspectives. ,vol. 104, pp. 741- 803 ,(1996) , 10.1289/EHP.96104S4741
Helena Taskinen, Ahti Anttila, M L Lindbohm, M Sallmen, Kari Hemminki, Spontaneous abortions and congenital malformations among the wives of men occupationally exposed to organic solvents. Scandinavian Journal of Work, Environment & Health. ,vol. 15, pp. 345- 352 ,(1989) , 10.5271/SJWEH.1839
José E. Sánchez-Criado, Francisco Galiot, Carmina Bellido, Dolores Gonzalez, Maria Tébar, Hypothalamus-pituitary-ovarian axis in cyclic rats lacking progesterone actions. Biology of Reproduction. ,vol. 48, pp. 916- 925 ,(1993) , 10.1095/BIOLREPROD48.4.916
Aramandla Ramesh, Darryl B. Hood, Frank Inyang, Michael Greenwood, Alfred M. Nyanda, Anthony E. Archibong, Maurice E. Knuckles, Comparative Metabolism, Bioavailability, and Toxicokinetics of Benzo[ a ]pyrene in Rats After Acute Oral, Inhalation, and Intravenous Administration Polycyclic Aromatic Compounds. ,vol. 22, pp. 969- 980 ,(2002) , 10.1080/10406630290104121
Samir S Raychoudhury, Dana Kubinski, Polycyclic aromatic hydrocarbon-induced cytotoxicity in cultured rat Sertoli cells involves differential apoptotic response. Environmental Health Perspectives. ,vol. 111, pp. 33- 38 ,(2002) , 10.1289/EHP.5458
R M Sharpe, J S Fisher, M M Millar, S Jobling, J P Sumpter, Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production. Environmental Health Perspectives. ,vol. 103, pp. 1136- 1143 ,(1995) , 10.1289/EHP.951031136
G. D. Charles, Activity of Benzo[a]pyrene and Its Hydroxylated Metabolites in an Estrogen Receptor-α Reporter Gene Assay Toxicological Sciences. ,vol. 55, pp. 320- 326 ,(2000) , 10.1093/TOXSCI/55.2.320
Kathleen F Arcaro, Patrick W O’Keefe, YI Yang, William Clayton, John F Gierthy, Antiestrogenicity of environmental polycyclic aromatic hydrocarbons in human breast cancer cells Toxicology. ,vol. 133, pp. 115- 127 ,(1999) , 10.1016/S0300-483X(99)00018-9
Karen M. Mackenzie, D. Murray Angevine, Infertility in Mice Exposed in utero to Benzo(a)pyrene Biology of Reproduction. ,vol. 24, pp. 183- 191 ,(1981) , 10.1095/BIOLREPROD24.1.183
Harry Fisch, Erik T. Goluboff, John H. Olson, Joseph Feldshuh, Stephen J. Broder, David H. Barad, Semen analyses in 1,283 men from the United States over a 25-year period: no decline in quality Fertility and Sterility. ,vol. 65, pp. 1009- 1014 ,(1996) , 10.1016/S0015-0282(16)58278-8