Silver nanoparticles and their orthopaedic applications

摘要: Implant-associated infection is a major source of morbidity in orthopaedic surgery. There has been extensive research into the development materials that prevent biofilm formation, and hence, reduce risk infection. Silver nanoparticle technology receiving much interest field orthopaedics for its antimicrobial properties, results studies to date are encouraging. Antimicrobial effects have seen when silver nanoparticles used trauma implants, tumour prostheses, bone cement, also combined with hydroxyapatite coatings. Although there promising vitro vivo studies, number clinical remains small. Future will be required explore further possible side associated nanoparticles, ensure their use an effective biocompatible manner. Here we present review current literature relating production nanosilver medical use, applications.