Surveillance of antimicrobial resistance - what, how and whither?

摘要: Objective To express the views of a working party held to consider antibiotic resistance surveillance systems, their strengths and weaknesses, current future applications. Methods The participants, all whom were experienced in this field, discussed development systems relation increasing prevalence antibacterial agents interest shown by many official bodies, both human veterinary fields. problems inherent considered together with applications different systems. Results properties good defined. Surveillance vary widely from those narrow base, focusing on few organisms one disease area, covering diseases, (including normal flora) compounds. Whatever design, they should be able detect significant differences shifts susceptibility various agents, information derived them reach as interested parties possible timely manner. In using decide strategies, criteria for action need determined pragmatic consensus. Funding remains major problem, large studies being supported bodies spite professed enthusiasm surveillance. consequence, are funded pharmaceutical industry necessity restricted focus. Conclusions Antibiotic can well planned executed. Many suffer well-recognized but uncorrected biases. Consortium funding will necessary schemes successful. There is no 'ideal' system.