PI3K/mTOR Dual Inhibitor, LY3023414, Demonstrates Potent Antitumor Efficacy Against Esophageal Adenocarcinoma in a Rat Model.

作者: Ali H. Zaidi , Juliann E. Kosovec , Daisuke Matsui , Ashten N. Omstead , Moses Raj

DOI: 10.1097/SLA.0000000000001908

关键词:

摘要: Objective:The purpose of the current study is to determine efficacy a PI3K/mTOR dual inhibitor, LY3023414, on established EAC in an vivo model.Background:Esophageal adenocarcinoma (EAC) highly lethal cancer with limited treatment options. The pathway upregulated

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