Low handgrip strength is a predictor of osteoporotic fractures: cross-sectional and prospective evidence from the Hong Kong Osteoporosis Study.

摘要: Handgrip strength (HGS) is a potentially useful objective parameter to predict fracture since it an indicator of general muscle and associated with fragility propensity fall. Our was examine the association HGS fracture, evaluate accuracy in predicting incident identify subjects at risk fracture. We analyzed cross-sectional cohort 2,793 (1,217 men 1,576 women aged 50–101 years) subset 1,702 which were followed for total 4,855 person-years. The primary outcome measures prevalent fractures major fractures. Each standard deviation (SD) reduction 1.24-fold increased odds clinical even after adjustment other factors. A similar result obtained prospective each SD being 1.57-fold hazard ratio combination femoral neck bone mineral density (FN BMD) T-score values (combined T-score), together factors, had better predictive power than FN BMD or alone In addition, combined has sensitivity specificity incidence alone. This study first compare ability BMD. showed that independent factor Compared using −2.5 alone, comparable BMD, may be extra improved specificity.