Prevalence of human immunodeficiency virus and its association with hepatitis B, C, and D virus infections among incarcerated male substance abusers in Taiwan.

摘要: Taiwan has been facing a rising epidemic of human immunodeficiency virus (HIV) infection since 2004. Injection drug users comprised 38.5% accumulated HIV cases by 2007. This cross-sectional study investigated the seroprevalence hepatitis B (HBV), C (HCV), D (HDV), and in 753 male substance who were detained detoxification center Taoyuan, Taiwan. The subjects enrolled into consecutively between February October, 2005. rates antibodies, HCV HBV surface antigens among all subjects, HDV antibodies carriers 6.9% (95% confidence interval [CI]: 5.19–8.95), 30.5% CI: 27.23–33.93), 16.9% 14.24–19.71) 13.7% 8.19–21.04), respectively. Subjects heroin injection group had significantly higher infection, superinfection (25.5%, 89.6%, 38.7%) than those non-injection (0.9%, 24.5%, 6.25%), methamphetamine (0.3%, 8.1%, 6.7%), club (1%, 3%, 0%; P < 0.001). odds HCV, HIV, or 74.7, 63.8, 11.1 higher, respectively, for (P < 0.0001). Compared to HIV-negative individuals, being injector co-infections 64-fold 149-fold HIV-positive individuals. impact HBV, on should be monitored closely. J. Med. Virol. 81:973–978, 2009. © 2009 Wiley-Liss, Inc.