Association between variant amyloid deposits and motor deficits in FAD-associated presenilin-1 mutations: A systematic review.
作者： Shuting Zhang , Chunyan Lei , Peng Liu , Mingming Zhang , Wendan Tao
DOI: 10.1016/J.NEUBIOREV.2015.07.003
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摘要: Abstract Background The variant amyloid deposits (VAD) include cotton wool plaques and diffuse plaques, which are associated with various motor deficits ( e.g. spastic paraparesis, myoclonus, parkinsonism ataxia). VADs have been repeatedly identified in presenilin 1 (PSEN1) mutations. It is still unknown the effect of VAD on as well course Alzheimer's disease (AD). Methods We conducted a systematic review literature using MEDLINE, AD&FTDMDB China National Knowledge Infrastructure database. Results A total 46 studies 84 patients were included. found that odds ratio group (56 patients) was 4.231 times non-VAD (28 patients). Moreover, displayed older age onset (42.80 ± 9.12 years) longer duration (9.05 ± 4.75 diseases. Conclusions These results suggested might be increased occurrence deficits. act protective modifier AD.
sci-hub.se 参考文章(130)
Henry Houlden, Matt Baker, Eileen McGowan, Patrick Lewis, Mike Hutton, Richard Crook, Nicholas W. Wood, Samir Kumar-Singh, Jennian Geddes, Michael Swash, Francesco Scaravilli, Janice L. Holton, Tammaryn Lashley, Taisuke Tomita, Tadafumi Hashimoto, Auli Verkkoniemi, Hannu Kalimo, Mirja Somer, Anders Paetau, Jean-Jacques Martin, Christine Van Broeckhoven, Todd Golde, John Hardy, Matti Haltia, Tamas Revesz, Variant Alzheimer's disease with spastic paraparesis and cotton wool plaques is caused by PS-1 mutations that lead to exceptionally high amyloid-beta concentrations Annals of Neurology. ,vol. 48, pp. 806- 808 ,(2000) , 10.1002/1531-8249(200011)48:5<806::AID-ANA18>3.0.CO;2-F
Howard Jay Aizenstein, Robert D. Nebes, Judith A. Saxton, Julie C. Price, Chester A. Mathis, Nicholas D. Tsopelas, Scott K. Ziolko, Jeffrey A. James, Beth E. Snitz, Patricia R. Houck, Wenzhu Bi, Ann D. Cohen, Brian J. Lopresti, Steven T. DeKosky, Edythe M. Halligan, William E. Klunk, Frequent Amyloid Deposition Without Significant Cognitive Impairment Among the Elderly JAMA Neurology. ,vol. 65, pp. 1509- 1517 ,(2008) , 10.1001/ARCHNEUR.65.11.1509
Sylvain Lesné, Ming Teng Koh, Linda Kotilinek, Rakez Kayed, Charles G. Glabe, Austin Yang, Michela Gallagher, Karen H. Ashe, A specific amyloid-β protein assembly in the brain impairs memory Nature. ,vol. 440, pp. 352- 357 ,(2006) , 10.1038/NATURE04533
Nobumasa Takasugi, Taisuke Tomita, Ikuo Hayashi, Makiko Tsuruoka, Manabu Niimura, Yasuko Takahashi, Gopal Thinakaran, Takeshi Iwatsubo, The role of presenilin cofactors in the gamma-secretase complex. Nature. ,vol. 422, pp. 438- 441 ,(2003) , 10.1038/NATURE01506
J.-C. Pechère, P. Rohner, M. Peebo, D. P. Lew, R. Auckenthaler, Comparative in-vitro activity of new quinolones against clinical isolates and resistant mutants Journal of Antimicrobial Chemotherapy. ,vol. 29, pp. 41- 48 ,(1992) , 10.1093/JAC/29.1.41
Sushil Sharma, Rais, Sandhu, Nel, Manuchair Ebadi, Clinical significance of metallothioneins in cell therapy and nanomedicine International Journal of Nanomedicine. ,vol. 8, pp. 1477- 1488 ,(2013) , 10.2147/IJN.S42019
P. Moretti, A. P. Lieberman, E. A. Wilde, B. I. Giordani, K. J. Kluin, R. A. Koeppe, S. Minoshima, D. E. Kuhl, W. K. Seltzer, N. L. Foster, Novel insertional presenilin 1 mutation causing Alzheimer disease with spastic paraparesis. Neurology. ,vol. 62, pp. 1865- 1868 ,(2004) , 10.1212/01.WNL.0000126447.91111.A1
Austin J. Yang, Mary Knauer, Debra A. Burdick, Charles Glabe, Intracellular Aβ1-42 Aggregates Stimulate the Accumulation of Stable, Insoluble Amyloidogenic Fragments of the Amyloid Precursor Protein in Transfected Cells Journal of Biological Chemistry. ,vol. 270, pp. 14786- 14792 ,(1995) , 10.1074/JBC.270.24.14786
Marco Canevelli, Paola Piscopo, Giuseppina Talarico, Nicola Vanacore, Alessandro Blasimme, Alessio Crestini, Giuseppe Tosto, Fernanda Troili, Gian Luigi Lenzi, Annamaria Confaloni, Giuseppe Bruno, Familial Alzheimer's disease sustained by presenilin 2 mutations: systematic review of literature and genotype-phenotype correlation. Neuroscience & Biobehavioral Reviews. ,vol. 42, pp. 170- 179 ,(2014) , 10.1016/J.NEUBIOREV.2014.02.010
Jie Kang, Hans-Georg Lemaire, Axel Unterbeck, J. Michael Salbaum, Colin L. Masters, Karl-Heinz Grzeschik, Gerd Multhaup, Konrad Beyreuther, Benno Müller-Hill, The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor Nature. ,vol. 325, pp. 733- 736 ,(1987) , 10.1038/325733A0