The effect of the extracts of Echinacea purpurea and Sambucus nigra (black elderberry) on virus shedding in H9N2 avian influenza infected chickens.

摘要: Summary Previous studies have shown antiviral effect of Echinacea and elderberry preparations against human influenza viruses in vitro. To investigate the vivo these herbs on avian H9N2 virus, amantadine two standardized commercial extracts purpurea (EF) Sambucus nigra (SAM) were used broiler chickens infected with strain virus. EF, SAM added to drinking water different groups for 7 days starting 8 h after intranasal inoculation challenged virus prophylaxis group EF 10 5 before challenge time. During post infection (PI) days, titer tracheal mucosa faeces quantified using quantitative real-time PCR. The untreated showed highest faecal day 3 PI. was not detected negative control during course experiment. Prophylaxis administration considerably reduced all Although overall samples low, treatment apparently quantity positive comparison EF-treated groups. This study indicates that chicken can reduce shedding from trachea faeces.