Macrophage-Mediated Cytotoxicity
作者： Penelope J. Duerksen-Hughes , Linda R. Gooding
DOI: 10.1007/978-1-4684-6814-4_42
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摘要: Macrophages are among the most versatile and multifunctional of cells. Their phagocytic ability is an essential part nonspecific immune defense against microorganisms, macrophages also required for specific responses, mediated by T B cells, to occur. In addition, manufacture release a wide variety substances with many different functions (for review, see Nathan, 1987). Perhaps remarkable thing about their differentiate between normal transformed infected selectively leave cells unharmed while killing or (Fidler Schroit, 1988). Thus, not only can discriminate self nonself, but often distinguish abnormal self. This chapter will examine cytotoxic activity both in vivo vitro.
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