The roles of nuclear focal adhesion kinase (FAK) on Cancer: a focused review.
作者： Jin Zhou , Qian Yi , Liling Tang
DOI: 10.1186/S13046-019-1265-1
关键词:
摘要: … of nuclear FAK in regulating gene expression. In addition, the use of FAK inhibitors to target nuclear FAK … Since FAK has a nuclear export signal, a nuclear localization signal, and the …
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Yu.M. Efremov, A.A. Dokrunova, A.V. Efremenko, M.P. Kirpichnikov, K.V. Shaitan, O.S. Sokolova, Distinct impact of targeted actin cytoskeleton reorganization on mechanical properties of normal and malignant cells Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. ,vol. 1853, pp. 3117- 3125 ,(2015) , 10.1016/J.BBAMCR.2015.05.008
Bert Vogelstein, David Lane, Arnold J. Levine, Surfing the p53 network Nature. ,vol. 408, pp. 307- 310 ,(2000) , 10.1038/35042675
Jonna Alanko, Anja Mai, Guillaume Jacquemet, Kristine Schauer, Riina Kaukonen, Markku Saari, Bruno Goud, Johanna Ivaska, Integrin endosomal signalling suppresses anoikis. Nature Cell Biology. ,vol. 17, pp. 1412- 1421 ,(2015) , 10.1038/NCB3250
Daniel Lietha, Xinming Cai, Derek F.J. Ceccarelli, Yiqun Li, Michael D. Schaller, Michael J. Eck, Structural Basis for the Autoinhibition of Focal Adhesion Kinase Cell. ,vol. 129, pp. 1177- 1187 ,(2007) , 10.1016/J.CELL.2007.05.041
Lauren A. Gillory, Jerry E. Stewart, Michael L. Megison, Alicia M. Waters, Elizabeth A. Beierle, Focal adhesion kinase and p53 synergistically decrease neuroblastoma cell survival Journal of Surgical Research. ,vol. 196, pp. 339- 349 ,(2015) , 10.1016/J.JSS.2015.03.021
Pascal Dao, Rafika Jarray, Johanne Le Coq, Daniel Lietha, Ali Loukaci, Yves Lepelletier, Réda Hadj-Slimane, Christiane Garbay, Françoise Raynaud, Huixiong Chen, Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity Bioorganic & Medicinal Chemistry Letters. ,vol. 23, pp. 4552- 4556 ,(2013) , 10.1016/J.BMCL.2013.06.038
Hyunho Yoon, Joshua P. Dehart, James M. Murphy, Ssang-Taek Steve Lim, Understanding the Roles of FAK in Cancer Inhibitors, Genetic Models, and New Insights Journal of Histochemistry and Cytochemistry. ,vol. 63, pp. 114- 128 ,(2015) , 10.1369/0022155414561498
William G Cance, Elena Kurenova, Timothy Marlowe, Vita Golubovskaya, Disrupting the scaffold to improve focal adhesion kinase-targeted cancer therapeutics. Science Signaling. ,vol. 6, pp. 2004021- ,(2013) , 10.1126/SCISIGNAL.2004021
R. Kleene, M. Mzoughi, G. Joshi, I. Kalus, U. Bormann, C. Schulze, M.-F. Xiao, A. Dityatev, M. Schachner, NCAM-Induced Neurite Outgrowth Depends on Binding of Calmodulin to NCAM and on Nuclear Import of NCAM and fak Fragments The Journal of Neuroscience. ,vol. 30, pp. 10784- 10798 ,(2010) , 10.1523/JNEUROSCI.0297-10.2010
Athar H Chishti, Anthony C Kim, Shirin M Marfatia, Mohini Lutchman, Manjit Hanspal, Hitesh Jindal, Shih-Chun Liu, Philip S Low, Guy A Rouleau, Narla Mohandas, Joel A Chasis, John G Conboy, Phillipe Gascard, Yuichi Takakuwa, Shu-Ching Huang, Edward J Benz Jr, Anthony Bretscher, Richard G Fehon, James F Gusella, Vijaya Ramesh, Frank Solomon, Vincent T Marchesi, Shoichiro Tsukita, Sachiko Tsukita, Monique Arpin, Daniel Louvard, Nicholas K Tonks, James M Anderson, Alan S Fanning, Peter J Bryant, Daniel F Woods, Kevin B Hoover, The FERM domain: A unique module involved in the linkage of cytoplasmic proteins to the membrane Trends in Biochemical Sciences. ,vol. 23, pp. 281- 282 ,(1998) , 10.1016/S0968-0004(98)01237-7