作者: James J. Prete , Bradley R. Prestidge , William S. Bice , Donald F. Dubois , Laura A. Hotchkiss
DOI: 10.1002/(SICI)1520-6823(1998)6:2<90::AID-ROI4>3.0.CO;2-C
关键词:
摘要: The purpose of this work was to investigate how a recently developed MRI-based post-implant dosimetric analysis technique for ultrasound guided transperineal interstitial permanent prostate brachytherapy (TIPPB) compared with the currently accepted CT-based technique. study based upon 3-mm MRI and CT scans 15 patients who had received either 125I or 103Pd implantation. All images were acquired on post-operative day 1 within hr each other. Prostate volumes determined by same physician. Sources digitized calculations performed using an in-house treatment planning system nearest neighbor seed sorting routine AAPM TG43 formalism. volume, geometric source distribution spread (rcom), dose volume histogram (DVH), tumor control probability (TCP) from both image sets. Differences in localization evaluated comparing prescription isodose volumes. through prostate-specific DVH TCP comparisons. as larger than that average +9.1% (R = 0.70). Calculated rcom smaller −0.9 mm 0.81) . Isodose at 80, 90, 100, 150% differed +2.5, +2.9, −2.9, +4.8%, respectively 0.97, 0.98, 0.91). Percentage encompassed −0.9, −0.1%, 0.34, 0.35, 0.35). −0.8% 0.37). results further support our initial findings may be used reliably localize implanted sources TIPPB. This also demonstrated is possible. However, it evident differences can result significantly different assessments coverage. There clearly need quantify between these two imaging modalities application address whether greater accuracy describing dose-volume relationship improvements visualization gland will translate into improved correlation outcome. Radiat. Oncol. Invest. 6:90–96, 1998. Published 1998 Wiley-Liss, Inc.