ASSOCIATION BETWEEN SERUM SELENIUM AND THE RISK OF CANCER

作者: JUKKA T. SALONEN , GEORG ALFTHAN , JUSSI K. HUTTUNEN , PEKKA PUSKA

DOI: 10.1093/OXFORDJOURNALS.AJE.A113898

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摘要: A matched-pair analysis was conducted with data based on a prospective six-year follow-up of random population sample to study the association between serum selenium and risk cancer. Case-control pairs were from population, after exclusions, 8,113 persons examined in 1972 two counties eastern Finland. Cases 31- 59-year-old men women initially free One control matched each case according age, gender, daily tobacco consumption, cholesterol concentration. The mean 128 cases 50.5 micrograms/liter that controls 54.3 (p = 0.012 for difference). When residual variation consumption as well four other possible confounders allowed multiple logistic model, less than 45 associated relative cancer 3.1 (95% confidence interval, 1.5-6.7, p 0.01). These support hypothesis deficiency increases certain cancers middle-aged persons.

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