IMPROVING EFFICACY OF ADENOVIRAL CANCER GENE THERAPY

Naoya Koizumi, Kenji Kawabata, Fuminori Sakurai, Yoshiteru Watanabe, Takao Hayakawa, Hiroyuki Mizuguchi, Modified adenoviral vectors ablated for coxsackievirus-adenovirus receptor, alphav integrin, and heparan sulfate binding reduce in vivo tissue transduction and toxicity. Human Gene Therapy. ,vol. 17, pp. 264- 279 ,(2006) , 10.1089/HUM.2006.17.264

Akira Matsumori, Ryosuke Nishio, Yoshisuke Nose, Calcium channel blockers differentially modulate cytokine production by peripheral blood mononuclear cells. Japanese Circulation Journal-english Edition. ,vol. 74, pp. 567- 571 ,(2010) , 10.1253/CIRCJ.CJ-09-0467

Alena Gros, Cristina Puig, Sonia Guedan, Juan José Rojas, Ramon Alemany, Manel Cascallo, Verapamil Enhances the Antitumoral Efficacy of Oncolytic Adenoviruses Molecular Therapy. ,vol. 18, pp. 903- 911 ,(2010) , 10.1038/MT.2010.22

Konstantin Doronin, Karoly Toth, Mohan Kuppuswamy, Peter Krajcsi, Ann E. Tollefson, William S.M. Wold, Overexpression of the ADP (E3-11.6K) protein increases cell lysis and spread of adenovirus. Virology. ,vol. 305, pp. 378- 387 ,(2003) , 10.1006/VIRO.2002.1772

Elanchezhiyan Manickan, Jeffrey S. Smith, Jie Tian, Thomas L. Eggerman, Jay N. Lozier, Jacqueline Muller, Andrew P. Byrnes, Rapid Kupffer cell death after intravenous injection of adenovirus vectors Molecular Therapy. ,vol. 13, pp. 108- 117 ,(2006) , 10.1016/J.YMTHE.2005.08.007

Anna Kanerva, Akseli Hemminki, Modified adenoviruses for cancer gene therapy. International Journal of Cancer. ,vol. 110, pp. 475- 480 ,(2004) , 10.1002/IJC.20129

Yuka Okada, Naoki Okada, Shinsaku Nakagawa, Hiroyuki Mizuguchi, Makiko Kanehira, Naoko Nishino, Koichi Takahashi, Nobuyasu Mizuno, Takao Hayakawa, Tadanori Mayumi, Fiber-mutant technique can augment gene transduction efficacy and anti-tumor effects against established murine melanoma by cytokine-gene therapy using adenovirus vectors Cancer Letters. ,vol. 177, pp. 57- 63 ,(2002) , 10.1016/S0304-3835(01)00768-6

Loretta L. Nielsen, Maya Gurnani, Jameel Syed, Janet Dell, Barbara Hartman, Mark Cartwright, Robert C. Johnson, Recombinant E1-Deleted Adenovirus-Mediated Gene Therapy for Cancer: Efficacy Studies with p53 Tumor Suppressor Gene and Liver Histology in Tumor Xenograft Models Human Gene Therapy. ,vol. 9, pp. 681- 694 ,(1998) , 10.1089/HUM.1998.9.5-681

Rosa Maria Diaz, Feorillo Galivo, Timothy Kottke, Phonphimon Wongthida, Jian Qiao, Jill Thompson, Mikael Valdes, Glen Barber, Richard G. Vile, Oncolytic immunovirotherapy for melanoma using vesicular stomatitis virus. Cancer Research. ,vol. 67, pp. 2840- 2848 ,(2007) , 10.1158/0008-5472.CAN-06-3974

Alan L. Parker, John H. McVey, Jessica H. Doctor, Oscar Lopez-Franco, Simon N. Waddington, Menzo J. E. Havenga, Stuart A. Nicklin, Andrew H. Baker, Influence of Coagulation Factor Zymogens on the Infectivity of Adenoviruses Pseudotyped with Fibers from Subgroup D Journal of Virology. ,vol. 81, pp. 3627- 3631 ,(2007) , 10.1128/JVI.02786-06