作者: Jayne A. Morris-Thurgood
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摘要: Because the ventricles share a common septum, filling of one may influence compliance other, phenomenon known as direct diastolic ventricular interaction (DVI). This is markedly enhanced when force exerted by surrounding pericardium raised (pericardial constraint). In health, in resting state, we operate near top flat component J-shaped pericardial stress-strain relation. Therefore, constraint (and hence DVI) only minor. When right volume/pressure acutely increases, such during exercise, massive pulmonary embolism, or infarction, increases and significant DVI develops. this setting, measured left intracavitary pressure overestimates true pressure, because external forces must be subtracted. Although can grow chronic cardiac enlargement, present evidence that certain disease processes, including heart failure, also important.