Mating system and avpr1a promoter variation in primates

摘要: It has been suggested that primate mating and social behaviours may be influenced by variation in promoter region repetitive DNA of the vasopressin receptor 1a gene (avpr1a). We show male behaviour does not covary a simple way with 12 Old World primates. found one microsatellite (L553 bp upstream) was present all species, irrespective their behaviour. By contrast, two microsatellites (L3956 L3625 were only some yet this did correlate These findings agree recent comparative analysis voles avpr1a generally explain Phylogenetic revealed GAGTA motif independently deleted three times involved another larger deletion. Importantly, presence/absence leads to changes predicted transcription factor-binding sites. Given repeated loss motif, we speculate it might functional relevance. suggest such nonrepetitive variation, either indels or sequence are likely important explaining interspecific expression.