Hypertrophic cardiomyopathy in children with end-stage renal disease and hypertension.

摘要: Cardiac function was evaluated by echocardiography (echo) in ten paediatric patients, 2.5 to 15 years of age, maintained on chronic dialysis. All had moderate severe hypertension despite intensive antihypertensive medication. Four patients showed, echo, asymmetric septal hypertrophy (ASH) typical hypertrophic cardiomyopathy (HCM). Two also signs suggestive outflow obstruction. Primary excluded a family survey first-degree relatives. The incidence HCM our series is impressive (40%). pathogenesis this cardiac lesion uraemia unknown; long-standing may play role. Early recognition form has important clinical considerations. Echo should become routine examination the diagnosis, follow-up, and treatment children with end-stage renal disease.