Investigating laminar mixing in high pressure microfluidic systems
作者： Fan Zhang , Arnaud Erriguible , Samuel Marre
DOI: 10.1016/J.CES.2019.03.063
关键词:
摘要: Abstract In this study, the hydrodynamic behavior of coflowing fluids CO2 and ethanol has been investigated in a high-pressure microfluidic reactor working at supercritical conditions, which two are completely miscible. The velocity field measured by Micro Particle Image Velocimetry ( μ PIV) for different temperatures between 20 50 °C fixed pressure 100 bar. Meanwhile, we have developed model to investigate numerically mixing. By comparing experimental results three-dimensional numerical simulation, mixing validated laminar coflow micromixer. order understand condition effects, several parameters investigated, namely: Reynolds number, temperature CO2/ethanol ratio. A time constant is defined using segregation intensity curve later used characterize quality. characteristic related energy dissipation rate ∊ , similarly stretching efficiency previous studies. quality eventually analyzed term index time.
sci-hub.se 参考文章(25)
A. Montes, C. Pereyra, E. J. Martínez de la Ossa, Screening design of experiment applied to the supercritical antisolvent precipitation of quercetin Journal of Supercritical Fluids. ,vol. 104, pp. 10- 18 ,(2015) , 10.1016/J.SUPFLU.2015.05.019
Yuya Maeta, Masaki Ota, Yoshiyuki Sato, Richard Lee Smith, Hiroshi Inomata, Measurements of vapor–liquid equilibrium in both binary carbon dioxide–ethanol and ternary carbon dioxide–ethanol–water systems with a newly developed flow-type apparatus Fluid Phase Equilibria. ,vol. 405, pp. 96- 100 ,(2015) , 10.1016/J.FLUID.2015.07.025
Robert D. Falgout, Ulrike Meier Yang, hypre: A Library of High Performance Preconditioners international conference on computational science. pp. 632- 641 ,(2002) , 10.1007/3-540-47789-6_66
Matthias Rossmann, Andreas Braeuer, Eberhard Schluecker, Supercritical antisolvent micronization of PVP and ibuprofen sodium towards tailored solid dispersions Journal of Supercritical Fluids. ,vol. 89, pp. 16- 27 ,(2014) , 10.1016/J.SUPFLU.2014.02.010
Ricardo Couto, Sylvain Chambon, Cyril Aymonier, Emmanuel Mignard, Bertrand Pavageau, Arnaud Erriguible, Samuel Marre, Microfluidic supercritical antisolvent continuous processing and direct spray-coating of poly(3-hexylthiophene) nanoparticles for OFET devices. Chemical Communications. ,vol. 51, pp. 1008- 1011 ,(2015) , 10.1039/C4CC07878K
Arnaud Erriguible, Tarik Fadli, Pascale Subra-Paternault, A complete 3D simulation of a crystallization process induced by supercritical CO2 to predict particle size Computers & Chemical Engineering. ,vol. 52, pp. 1- 9 ,(2013) , 10.1016/J.COMPCHEMENG.2012.12.002
Joëlle Aubin, Montse Ferrando, Vladimir Jiricny, Current methods for characterising mixing and flow in microchannels Chemical Engineering Science. ,vol. 65, pp. 2065- 2093 ,(2010) , 10.1016/J.CES.2009.12.001
J. BALDYGA, J.R. BOURNE, A FLUID MECHANICAL APPROACH TO TURBULENT MIXING AND CHEMICAL REACTION PART III COMPUTATIONAL AND EXPERIMENTAL RESULTS FOR THE NEW MICROMIXING MODEL Chemical Engineering Communications. ,vol. 28, pp. 259- 281 ,(1984) , 10.1080/00986448408940137
Jerzy Bałdyga, Rafał Czarnocki, Boris Y. Shekunov, Keith B. Smith, Particle formation in supercritical fluids—Scale-up problem Chemical Engineering Research & Design. ,vol. 88, pp. 331- 341 ,(2010) , 10.1016/J.CHERD.2010.01.019
L. Falk, J.-M. Commenge, Performance comparison of micromixers Chemical Engineering Science. ,vol. 65, pp. 405- 411 ,(2010) , 10.1016/J.CES.2009.05.045