Molecular Mechanism and Potential Targets for Blocking HPV-Induced Lesion Development.
作者： E. Guzmán-Olea , V. H. Bermúdez-Morales , O. Peralta-Zaragoza , K. Torres-Poveda , V. Madrid-Marina
DOI: 10.1155/2012/278312
关键词:
摘要: Persistent infection with high-risk HPV is the etiologic agent associated development of cervical cancer (CC) development. However, environmental, social, epidemiological, genetic, and host factors may have a joint influence on risk disease progression. Cervical lesions caused by can be removed naturally immune response only small percentage progress to cancer; thus, essential for control precursor CC. We present review recent research molecular mechanisms that allow HPV-infected cells evade surveillance potential targets therapy inhibit tumor escape.
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