Lymphoplasmacytic sclerosing pancreatitis: inflammatory mimic of pancreatic carcinoma.

摘要: Lymphoplasmacytic sclerosing pancreatitis (LP) is a rare cause of benign mass lesions the pancreas that can resemble adenocarcinoma. This study evaluates and classifies series patients with LP. Patients pancreatic disease were identified from prospective database, these cases reviewed to identify subdivided into two groups: (1) classic LP, which included those who had all four characteristic histologic features including lymphoplasmacytic infiltration pancreas, interstitial fibrosis, periductal inflammation, peri-phlebitis; (2) intermediate at least findings. Patient demographics, pathologic clinical features, outcome analyzed. From 1985 2001, total 1287 resections performed our institution, 159 for disease. Of these, 31 consistent presumed preoperative diagnosis carcinoma. Most presented jaundice (n = 21) or abdominal pain 7). In 29 patients, curative resection was possible. 28% (8/29) developed recurrence after resection: seven one recurrent (median time recurrence, 11 months; median follow up, 38 months). All appeared have biliary strictures direct cholangiography no patient malignancy. A review pathology reports 19 LP 12 there difference between groups. difficult differentiate carcinoma preoperatively. appear demonstrate similar behavior. Nearly third progressive course resection, 25% developing jaundice; thus close follow-up mandatory patients.