A possible association between influenza vaccination and small-vessel vasculitis.

摘要: We describe two patients who experienced small-vessel vasculitic syndromes after influenza immunization. Their illnesses were characterized by fever, arthralgias, and myalgias; uveitis optic neuritis occurred in one patient, while the other had palpable purpura, which histologically was proved to be a cutaneous necrotizing venulitis. No viral or bacterial infection, medications, underlying systemic rheumatic disease could implicated. To our knowledge, vasculitis occurring vaccination has not been previously reported. (Arch Intern Med140:847-848, 1980)