The role and clinical relevance of disseminated tumor cells in breast cancer.
作者： Malgorzata Banys , Natalia Krawczyk , Tanja Fehm
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摘要: Tumor cell dissemination is a common phenomenon observed in most cancers of epithelial origin. One-third breast cancer patients present with disseminated tumor cells (DTCs) bone marrow at time diagnosis; these patients, as well persistent DTCs, have significantly worse clinical outcome than DTC-negative patients. Since DTC phenotype may differ from the primary regard to ER and HER2 status, reevaluation predictive markers on DTCs optimize treatment choices. In review, we report relevance detection cancer.
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