EXAFS Spectroscopic Evidence for an FeO Unit in the Fe(IV) Intermediate Observed during Oxygen Activation by Taurine:α-Ketoglutarate Dioxygenase

作者: Pamela J. Riggs-Gelasco , John C. Price , Robert B. Guyer , Jessica H. Brehm , Eric W. Barr

DOI: 10.1021/JA048255Q

关键词:

摘要: The Fe(II)- and α-ketoglutarate-dependent dioxygenases catalyze hydroxylation reactions of considerable biomedical and environmental significance. Recently, the first oxidized iron …

参考文章(14)
M. H. Lim, J.-U. Rohde, A. Stubna, M. R. Bukowski, M. Costas, R. Y. N. Ho, E. Munck, W. Nam, L. Que, An FeIV=O complex of a tetradentate tripodal nonheme ligand. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 100, pp. 3665- 3670 ,(2003) , 10.1073/PNAS.0636830100
J E Penner-Hahn, T J McMurry, M Renner, L Latos-Grazynsky, K S Eble, I M Davis, A L Balch, J T Groves, J H Dawson, K O Hodgson, X-ray absorption spectroscopic studies of high valent iron porphyrins. Horseradish peroxidase compounds I and II and synthetic models. Journal of Biological Chemistry. ,vol. 258, pp. 12761- 12764 ,(1983) , 10.1016/S0021-9258(17)44029-4
Miquel Costas, Mark P. Mehn, Michael P. Jensen, Lawrence Que, Dioxygen Activation at Mononuclear Nonheme Iron Active Sites:  Enzymes, Models, and Intermediates Chemical Reviews. ,vol. 104, pp. 939- 986 ,(2004) , 10.1021/CR020628N
James E. Penner-Hahn, Kim. Smith Eble, Thomas J. McMurry, Mark. Renner, Alan L. Balch, John T. Groves, John H. Dawson, Keith O. Hodgson, Structural characterization of horseradish peroxidase using EXAFS spectroscopy: evidence for Fe=O ligation in compounds I and II Journal of the American Chemical Society. ,vol. 108, pp. 7819- 7825 ,(1986) , 10.1021/JA00284A054
Matthew J Ryle, Robert P Hausinger, Non-heme iron oxygenases. Current Opinion in Chemical Biology. ,vol. 6, pp. 193- 201 ,(2002) , 10.1016/S1367-5931(02)00302-2
James E. Penner-Hahn, Maurizio Benfatto, Britt Hedman, Tadashi Takahashi, Sebastian Doniach, John T. Groves, Keith O. Hodgson, Polarized x-ray absorption near-edge structure of highly oxidized chromium porphyrins Inorganic Chemistry. ,vol. 25, pp. 2255- 2259 ,(1986) , 10.1021/IC00233A032
Pamela J. Riggs-Gelasco, Rui Mei, Charles F. Yocum, James E. Penner-Hahn, Reduced derivatives of the Mn cluster in the oxygen-evolving complex of photosystem II: An EXAFS study Journal of the American Chemical Society. ,vol. 118, pp. 2387- 2399 ,(1996) , 10.1021/JA9504496
Denis A. Proshlyakov, Timothy F. Henshaw, Greta R. Monterosso, Matthew J. Ryle, Robert P. Hausinger, Direct Detection of Oxygen Intermediates in the Non-Heme Fe Enzyme Taurine/α-Ketoglutarate Dioxygenase Journal of the American Chemical Society. ,vol. 126, pp. 1022- 1023 ,(2004) , 10.1021/JA039113J