Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population.

作者: David R. Bangsberg , Frederick M. Hecht , Edwin D. Charlebois , Andrew R. Zolopa , Mark Holodniy

DOI: 10.1097/00002030-200003100-00008

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摘要: … The three measures of adherence led to similar estimates of the relationship between adherence and viral suppression. Adherence was a much stronger predictor of viral load than was drug resistance in this study. The relative strength of adherence vis-à-vis drug resistance as a predictor of virological response may vary according to the clinical setting, drug regimen and study population. In this study, however, it was observed that subjects with …

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