Oxidative Stress at the Crossroads Between Osteoarthritis and Metabolic Syndrome

摘要: This chapter focuses on the role of oxidative stress in osteoarthritis and metabolic syndrome with discussion mechanisms commonalities. We address molecular biology chondrocytes, synoviocytes, adipocytes, mitochondria as they relate to these two disorders. The final concerns epigenetic modulation a target for therapy osteoarthritis. In short, plays generation changes seen cartilage. As outlined below, may adversely impact not only loss maturational arrest chondrocytes but extracellular joint matrix well.