Antibiotic prophylaxis in anterior skull-base surgery: a survey of the North American Skull Base Society.

摘要: BACKGROUND There is a paucity of data evaluating antibiotic use in anterior skull-base surgery (ASBS). The goal this study was to determine prescribing patterns and factors that influence ASBS. METHODS An online-based survey distributed the membership North American Skull Base Society 2018. Outcomes included practitioner preference regarding intraoperative postoperative use, practice location environment, surgeon experience, patient influencing use. RESULTS were 208 respondents (25.6% response rate) which 182 (87.5%) performed ASBS; 60.4% academic institutions. Respondents neurosurgeons (59.3%) or otolaryngologists (40.7%), 75.3% fellowship-trained Most surgeons (95.0%) gave antibiotics. Academic 4 times more likely prescribe antibiotics than private practitioners (odds ratio [OR] 3.98; 95% confidence interval [CI], 1.53 10.36; p = 0.005). Among who did not routinely antibiotics, regression analysis indicated presence actively infected sinuses, transplantation, diabetes, human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS), pulmonary disease influenced decision-making (p < 0.03). Postoperative prescribed by 73.6% respondents. European 3 less (OR 0.34; CI, 0.15 0.80; 0.01). Regression modeling HIV/AIDS, cystic fibrosis, disease, as well absorbable packing decision 0.003). CONCLUSION This demonstrates significant variation intra- among performing Prospective randomized studies are necessary establish evidence-based guidelines for perioperative