摘要: High-density lipoproteins (HDL) are a population of apolipoprotein A-I-containing particles inversely correlated with the risk coronary heart disease (CHD) (Linsel-Nitschke and Tall 2005), but lower HDL cholesterol levels not uniformly associated excess cardiovascular risk, nor do they always confer protective benefit (Mahdy Ali et al. 2012). Further, has biological functions that transcend its antiatherogenic role; to paraphrase Einstein, “God” did create prevent atherosclerosis. In this chapter, I will present brief history HDL, focusing on discovery amphipathic helix, concept led development peptide mimetics.
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