Where's the high-grade cervical neoplasia? The importance of minimally abnormal Papanicolaou diagnoses
作者： W Kinney
DOI: 10.1016/S0029-7844(98)00080-5
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摘要: Abstract %Objective: To characterize the relative contributions of different abnormal Papanicolaou smear cytologic diagnoses in Bethesda System to subsequent histologic diagnosis high-grade cervical neoplasia. Methods: A total 46,009 nonpregnant female members Kaiser Permanente Health Plan, Northern California Region, were studied prospectively. The main outcome measures included routine and colposcopically directed tissue specimens. Results: Atypical squamous cells undetermined significance (ASCUS) was most common diagnosis, representing 3.6% number smears. Of cases histologically confirmed neoplasia present population, largest proportion (38.8%) women with smears showing ASCUS. Minimal abnormalities combined (ASCUS, atypical glandular significance, low-grade intraepithelial lesion) coincident 68.6% diagnosed this screening population. Conclusion: Recognition importance equivocal mild test emphasizes need for accurate cost-effective triage large population minimally diagnoses.
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