Cryoballoon ablation of pulmonary veins for paroxysmal atrial fibrillation: first results of the North American Arctic Front (STOP AF) pivotal trial.

作者: Douglas L Packer , Robert C Kowal , Kevin R Wheelan , James M Irwin , Jean Champagne

DOI: 10.1016/J.JACC.2012.11.064

关键词:

摘要: Objectives: This study sought to assess the safety and effectiveness of a novel cryoballoon ablation technology designed to achieve single-delivery pulmonary vein (PV) isolation. Background: Standard radiofrequency ablation is effective in eliminating atrial fibrillation (AF) but requires multiple lesion delivery at the risk of significant complications. Methods: Patients with documented symptomatic paroxysmal AF and previously failed therapy with≥ 1 membrane active antiarrhythmic drug underwent 2: 1 randomization to either cryoballoon …

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