Predictive, preventive, personalised and participatory periodontology: ‘the 5Ps age’ has already started

摘要: An impressive progress in dentistry has been recorded the last decades. In order to reconsider guidelines dentistry, it is required introduce new concepts of personalised patient treatments: wave predictive, preventive and medicine rapidly incoming dentistry. Worldwide dentists have make a big cultural effort changing actual ‘reactive’ therapeutic point view, belonging century, into futuristic ‘predictive’ one. The first cause tooth loss industrialised world periodontitis, Gram-negative anaerobic infection whose pathogenesis genetically determined characterised by complex immune reactions. Chairside diagnostic tests based on saliva, gingival crevicular fluid cell sampling are going be routinely used periodontists for approach diagnosis, monitoring, prognosis management periodontal patients. ‘5Ps’ (predictive, preventive, participatory periodontology) focuses early integrated diagnosis (genetic, microbiology, host-derived biomarker detection) active role which networked patients will shift from being mere passengers responsible drivers their health. this paper, we intend propose five levels (high-tech tools, genetic susceptibility, bacterial infection, host response factors tissue breakdown-derived products) evaluated with intention obtain clear picture vulnerability single individual periodontitis organise stratification different categories risk. Lab-on-a-chip (LOC) technology may soon become an important part efforts improve worldwide health developed nations as well underserved communities, resource-poor areas poor countries. use LOC devices inspection allow screened diseases settings other than periodontist practice, such at general practitioners, or dental hygienists. Personalised therapy tailored respect particular medical reality specific stratified ultimate target realised 5Ps approach. A long distance covered reach above targets, but pathway already clearly outlined.