Ultrafine organic aerosol particles inhaled by mice at low doses remain in lungs more than half a year

摘要: Experimental results of the second series experiments on penetration monodisperse polymeric particles, inhaled at low dose by mice, to different organs using direct way particle registration, based ultra-sensitive accelerator mass spectrometer (AMS), are presented. Polystyrene (PS) beads, composed radiocarbon-labeled styrene, were produced for testing them as model organic aerosols. Mice 14 C-PS aerosol 3·105 ultrafine particles per 1 cm3 30 minutes every day during 5 days. Long-term investigation showed that PS have been effectively accumulated in lungs with maximum content fifth postexposure, and also appeared liver exposure brain 30th experiments. No detected kidneys, spleen, excrements. Thirty-five millions remained after half a year postexposure showing extremely slow removal such from organ.