Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
作者： Houston F. Voss , Thomas R. Herrin , Jacob Plattner
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摘要: The present invention encompasses a method for determining ligands in test samples comprising intermixing with the sample ligand analog-irreversible enzyme inhibitor conjugate and binding protein bindable to wherein amount of bound by is related sample, said inactivating irreversible when analog portion conjugate; an which irreversibly inhibited unbound protein; substrate monitoring reaction. also includes conjugates useful as reagents practicing method. Methods are particularly drugs, hormones, like biological fluids.
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