Specific alleles at immune genes, rather than genome-wide heterozygosity, are related to immunity and survival in the critically endangered Attwater's prairie-chicken.
作者： Zachary W. Bateson , Susan C. Hammerly , Jeff A. Johnson , Michael E. Morrow , Linda A. Whittingham
DOI: 10.1111/MEC.13793
关键词:
摘要: The negative effects of inbreeding on fitness are serious concerns for populations endangered species. Reduced has been associated with lower genome-wide heterozygosity and immune gene diversity in the wild; however, it is rare that both types genetic measures included same study. Thus, often unclear whether variation due to general inbreeding, immunity-related genes or both. Here, we tested (20 990 SNPs) at nine were better predictors two (immune response survival) Attwater's prairie-chicken (Tympanuchus cupido attwateri). We found postrelease survival captive-bred birds was related alleles innate (Toll-like receptors, TLRs) adaptive (major histocompatibility complex, MHC) systems, but not heterozygosity. Likewise, time release TLR MHC alleles, Overall, this study demonstrates may serve as important markers when monitoring inbred some specific functional be than
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