Use of Animal Bioassay Data in Carcinogen Risk Assessment

作者: Elizabeth K. Weisburger

DOI: 10.1007/978-1-4684-5484-0_4

关键词:

摘要: Risk assessment generally comprises some or all of the following factors: hazard identification, dose-response assessment, exposure and risk characterization (National Research Council, 1983). Animal bioassays are fundamental in furnishing information directly relevant to first two these factors, identification assessment.

参考文章(36)
D. Krewski, Ian C. Munro, D. B. Clayson, Toxicological risk assessment CRC Press. ,(1985)
Gary D. Stoner, Elizabeth K. Weisburger, Michael B. Shimkin, Jeffrey C. Theiss, Test for Carcinogenicity of Organic Contaminants of United States Drinking Waters by Pulmonary Tumor Response in Strain A Mice Cancer Research. ,vol. 37, pp. 2717- 2720 ,(1977)
Michael B. Shimkin, Gary D. Stoner, Lung Tumors in Mice: Application to Carcinogenesis Bioassay Advances in Cancer Research. ,vol. 21, pp. 1- 58 ,(1975) , 10.1016/S0065-230X(08)60970-7
D. P. Griswold, A. E. Casey, E. K. Weisburger, J. H. Weisburger, The carcinogenicity of multiple intragastric doses of aromatic and heterocyclic nitro or amino derivatives in young female sprague-dawley rats. Cancer Research. ,vol. 28, pp. 924- 933 ,(1968)
Emerita N Alcantara, Elwood W Speckmann, None, Diet, nutrition, and cancer. The American Journal of Clinical Nutrition. ,vol. 29, pp. 1035- 1047 ,(1976) , 10.1093/AJCN/29.9.1035
Bioassay of 29 Alkylatlng Chemicals by the Pulmonary-Tumor Response In Strain A Mice Journal of the National Cancer Institute. ,vol. 36, pp. 915- 935 ,(1966) , 10.1093/JNCI/36.5.915
Carcinogenicity Tests of Certain Environmental and Industrial Chemicals Journal of the National Cancer Institute. ,vol. 67, pp. 75- 88 ,(1981) , 10.1093/JNCI/67.1.75
Roland L. Phillips, Role of Life-style and Dietary Habits in Risk of Cancer among Seventh-Day Adventists Cancer Research. ,vol. 35, pp. 3513- 3522 ,(1975)
F. M. Schabel, D. P. Griswold, A. E. Casey, E. K. Weisburger, J. H. Weisburger, On the Carcinogenicity of a Single Intragastric Dose of Hydrocarbons, Nitrosamines, Aromatic Amines, Dyes, Coumarins, and Miscellaneous Chemicals in Female Sprague-Dawley Rats Cancer Research. ,vol. 26, pp. 619- 625 ,(1966)
Elizabeth K. Weisburger, Techniques for Carcinogenicity Studies Cancer Research. ,vol. 41, pp. 3690- 3694 ,(1981)