Interstitial thermal ablation with a fast rotating dual-mode transducer

摘要: Interstitial ultrasound applicators can be a minimally invasive alternative for treating targets that are unresectable or inaccessible by extracorporeal methods. Dualmode transducers imaging and therapy were developed to address the constraints of miniaturized applicator real-time treatment monitoring. We propose an original strategy combines using dual-mode transducer rotating at 8 revolutions per second. Real-time B-mode was interrupted emit high-intensity over selected aperture. A full 360° image taken every 8th rotation Numerical simulations performed study effect on tissue heating, sequence temperature. With time-averaged surface intensity held 12 W/ cm2 maintain temperature below 66°C, higher field intensities deeper lesions produced narrower apertures. prototype system built tested in vitro samples porcine liver. Lesions up mm W/cm2 applied period 240 s aperture 40°. Apparent strain improved contrast between treated spared tissues, which could not differentiated images. appropriate limits output, deep thermal ablation feasible sustainable transducer.