Overview of Predictive Biomarkers and Integration of IHC into Molecular Pathology

摘要: With rapid advances in our understanding of molecular and genetic pathogenesis a continuous push for personalized medicine, assessment predictive prognostic biomarkers by immunohistochemistry (IHC) routine pathological diagnosis is evolving into new trend. As matter fact, many such tests have been incorporated the current diagnostic algorithm common cancers arising breast, lung, colon, stomach gastroesophageal junction, as well hematopoietic malignancy melanoma. Since all are representations unique events occurring tumor cells during carcinogenesis, this trend has prefaced an exciting era IHC clinical application.