Ultrasensitive Bisphenol A Field-Effect Transistor Sensor Using an Aptamer-Modified Multichannel Carbon Nanofiber Transducer

作者: Sung Gun Kim , Jun Seop Lee , Jaemoon Jun , Dong Hoon Shin , Jyongsik Jang

DOI: 10.1021/ACSAMI.5B11159

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摘要: Bisphenol A (BPA) is a known endocrine-disrupting compound (EDC) that has structure similar to of the hormone estrogen. Even low concentrations BPA are able bind estrogen receptors, thereby inducing severe diseases such as reproductive disorders, chronic diseases, and various types cancer. Despite serious effects, use remains widespread. Therefore, monitoring both dietary nondietary exposure important for human healthcare. Herein, we present field-effect transistor (FET) sensor using aptamer-modified multichannel carbon nanofibers (MCNFs) detect BPA. The MCNFs fabricated via single-nozzle electrospinning two immiscible polymer solutions followed by thermal treatment in an inert atmosphere. then oxidized solution HNO3 H2SO4 introduce carboxyl groups on surface fibers. carboxyl-functionalized (CMCNFs) immobilized amine-functionalized electrode substrate forming covalent bond, ...

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