Primary leptomeningeal T-cell lymphoblastic lymphoma: a rare cause of chronic meningitis.

作者: Arunmozhimaran Elavarasi , Rohit Bhatia , Sudheer Arava , Lalit Kumar

DOI: 10.1136/BCR-2020-236491

关键词:

摘要: Primary leptomeningeal lymphomatosis is a rare disease with only few hundred cases reported. We present patient relatively short history of 25 days headache followed by diplopia who was found to have primary T-cell lymphoma without evidence systemic lymphoma. The responded well chemotherapy along intrathecal medication and cranial irradiation returned completely normal state health. Not all chronic meningitis due infection or self-limiting inflammatory causes. It important consider as differential even in the absence constitutional features such loss weight, appetite, night sweats, lymphadenopathy hepatosplenomegaly. Central Nervous system (CNS) involvement cause meningitis, which eminently amenable treatment fatal if missed.

参考文章(5)
D. H. Lachance, B. P. O'Neill, D. R. Macdonald, K. A. Jaeckle, T. E. Witzig, C.-Y. Li, J. B. Posner, Primary leptomeningeal lymphoma: report of 9 cases, diagnosis with immunocytochemical analysis, and review of the literature. Neurology. ,vol. 41, pp. 95- 100 ,(1991) , 10.1212/WNL.41.1.95
Joshua Solomon Manusow, Matthew Lee-Wing, Jennifer Rahman, Andrew Mis, Primary leptomeningeal lymphoma masquerading as pseudotumor cerebri. Canadian Journal of Ophthalmology-journal Canadien D Ophtalmologie. ,vol. 44, ,(2009) , 10.3129/I09-063
E. Broussalis, M. Hutterer, K. Oppermann, P. Wipfler, G. Pilz, A. Harrer, E. Haschke-Becher, S. Golaszewski, U. Schönauer, S. Weis, M. Killer-Oberpfalzer, M. Mc Coy, E. Trinka, J. Kraus, Isolated leptomeningeal infiltration of a primary CNS B-cell lymphoma diagnosed by flow cytometry and confirmed by necropsy. Acta Neurologica Scandinavica. ,vol. 126, ,(2012) , 10.1111/J.1600-0404.2011.01630.X
Jennie W Taylor, Eoin P Flanagan, Brian P O'Neill, Tali Siegal, Antonio Omuro, Lisa DeAngelis, Joachim Baehring, Ryo Nishikawa, Fernando Pinto, Marc Chamberlain, Khe Hoang-Xuan, Alberto Gonzalez-Aguilar, Tracy Batchelor, Jean-Yves Blay, Agnieszka Korfel, Rebecca A Betensky, Maria-Beatriz S Lopes, David Schiff, None, Primary leptomeningeal lymphoma International Primary CNS Lymphoma Collaborative Group report Neurology. ,vol. 81, pp. 1690- 1696 ,(2013) , 10.1212/01.WNL.0000435302.02895.F3