Synthesis of enantiopure free and N-benzyloxycarbonyl-protected 3-substituted homotaurines from naturally occurring amino acids
作者： Yongpeng Zheng , Jiaxi Xu
DOI: 10.1016/J.TET.2014.05.098
关键词:
摘要: Abstract Enantiopure N-benzyloxycarbonyl-protected and free 3-substituted homotaurines were synthesized from naturally occurring amino acids via N-benzyloxycarbonyl protection, Arndt–Eistert homologation, reduction, esterification with thioacetic acid, oxidation performic acid. The current method is a convenient, practical, salt-free for the synthesis of enantiopure homotaurine moderate to good yields.
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