作者: Francisco Martínez-Abarca , Nicolás Toro
DOI: 10.1046/J.1365-2958.2000.02197.X
关键词:
摘要: Group II introns are large catalytic RNA molecules that act as mobile genetic elements. They were initially identified in the organelle genomes of lower eukaryotes and plants, it has been suggested they progenitors nuclear spliceosomal introns. self-splicing shown to be present bacteria 1993, since when various bacterial genome sequencing projects have led a significant increase number group intron sequences databases. However, few these characterized, most on basis their intron-encoded protein (IEP), with little data available concerning ribozyme/RNA structure. Their frequency prokaryotes is also unknown. We attempt here provide first comprehensive review based recent mechanistic studies.