Correlation of Hydrolysis and Desilylation of 2‐[(Trimethylsilyl)methyl]acrylate Derivatives in Aqueous Alkali Solutions
作者： Chiaki Kuroda , Takeshi Sunakawa , Yuichi Muguruma
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摘要: Hydrolysis and desilylation reaction of 2-[(trimethylsilyl)methyl]acrylate (=2-[(trimethylsilyl)methyl]prop-2-enoate) derivatives were studied to evaluate the effect presence/absence a further conjugating substituent (Schemes 3 4 Tables 1 2). The substrates having nonconjugating at acrylate moiety stable dilute alkali conditions, afforded simple hydrolysis products under concentrated conditions. In contrast, both occurred from bearing conjugated substituents skeleton. difference in reactivity can be explained terms stabilization intermediate anion.
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