Involvement of glutamate 268 in the active site of human liver mitochondrial (class 2) aldehyde dehydrogenase as probed by site-directed mutagenesis.

作者: Xinping Wang , Henry Weiner

DOI: 10.1021/BI00001A028

关键词:

摘要: … That is, an active site nucleophile attacks the aldehyde to form … residue at position 268 was mutated to other residues in … Neither NADH nor p-nitrophenol accumulated with mutants …

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